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Monday, 04 February 2019
Time Speaker Title Resources
09:30 to 10:45 Mrudula (NCBS, India) Basic elements of genetics and evolution: Genes, genomes, central dogma, polymorphism, genotype-phenotype correlation, inheritance
10:45 to 11:15 -- Tea/coffee break
11:15 to 12:30 Archana (JNCASR, India) (Basic Math lecture): calculus, vectors/matrices, probabiity distributions
12:30 to 13:30 -- Lunch
13:30 to 14:45 Deepa Agashe (NCBS, India) Problem set: Mendelian genetics, selection, mutations
14:45 to 15:00 -- Short break
15:00 to 16:15 Archana (JNCASR, India) Basic Math tutorial
16:15 to 16:30 -- Tea/coffee break
16:30 Deepa Agashe (NCBS, India) Journal club: Discuss Rainey and Travisano 1998
Tuesday, 05 February 2019
Time Speaker Title Resources
09:30 to 10:45 Vishwesha Guttal (IISc, India) Process of model building. Discrete-time population dynamical models: density-dependent and density-independent growth
10:45 to 11:15 -- Tea/coffee break
11:15 to 12:30 Uma Ramakrishnan (NCBS, India) Hardy-Weinberg equilibirum; estimating allele frequencies
12:30 to 13:30 -- Lunch
13:30 to 14:45 Vishwesha Guttal (IISc, India) Discrete-time logistic population model; linear stability analysis
14:45 to 15:00 -- Short break
15:00 to 16:15 Uma Ramakrishnan (NCBS, India) Basics of drift and migration. sampling and allele freq; Fst and wahlund effect
16:15 to 16:30 -- Tea/coffee break
16:30 Sumithra (IISc, India) Computer simulations of logistic population model. Discuss May 1976
Wednesday, 06 February 2019
Time Speaker Title Resources
09:30 to 10:45 Vishwesha Guttal (IISc, India) Discuss the proess of model building, purpose of models in light of results of logistic model. Introduce continuous time models
10:45 to 11:15 -- Tea/coffee break
11:15 to 12:30 Deepa Agashe (NCBS, India) Processes generating variation: Mutations, mutation rate, recombination, plasticity
12:30 to 13:30 -- Lunch
13:30 to 14:45 Vishwesha Guttal (IISc, India) Game theory: hawk-dove games, selfishness and cooperation
14:45 to 15:00 -- Short break
15:00 to 16:15 Deepa Agashe (NCBS, India) Problem set: Measuring variation, experimental and bioinformatics approaches
16:15 to 16:30 -- Tea/coffee break
16:30 -- Free time
Thursday, 07 February 2019
Time Speaker Title Resources
09:30 to 10:45 Vishwesha Guttal (IISc, India) Game theory: evolution of cooperation
10:45 to 11:15 -- Tea/coffee break
11:15 to 12:30 Kavita Jain (JNCASR, India) Basic evol forces; Random genetic drift; Fixation probability; Neutral coalescent
12:30 to 13:30 -- Lunch
13:30 to 14:45 Vishwesha Guttal (IISc, India) Game theory: exercises
14:45 to 15:00 -- Short break
15:00 to 16:15 Kavita Jain (JNCASR, India) Problem set: Deterministic models
16:15 to 16:30 -- Tea/coffee break
16:30 Kavita Jain (JNCASR, India) Journal club: Discuss Luria & Delbruck 1943, Servedio et al 2014
Friday, 08 February 2019
Time Speaker Title Resources
09:30 to 10:45 Uma Ramakrishnan (NCBS, India) Mutation and selection. Island-continent model and change in alelle freq. Different kinds of selection, w and w_bar; change in allele freq
10:45 to 11:15 -- Tea/coffee break
11:15 to 12:30 Uma Ramakrishnan (NCBS, India) problem set: HW. Migration/population structure
12:30 to 13:30 -- Lunch
13:30 to 14:45 Kavita Jain (JNCASR, India) Adaptation dynamics (Lenski experiment, clonal interference, epistasis)
14:45 to 15:00 -- Short break
15:00 to 16:15 Kavita Jain (JNCASR, India) Discussion of homework problems
16:15 to 16:30 -- Tea/coffee break
16:30 Uma Ramakrishnan (NCBS, India) Journal club: Discuss Foerster et al 2007, Rubidge et al 2012, and Barrett et al 2008
Saturday, 09 February 2019
Time Speaker Title Resources
09:30 to 10:45 Deepa Agashe (NCBS, India) Genome evolution: codon use, composition, copy number variation, non-coding sequences, epistasis, selfish elements
09:30 to 10:45 -- Tea/coffee break
11:15 to 12:30 Uma Ramakrishnan (NCBS, India) Simulations with drift, explore colaescent models and micro-evol processes under coalsecent
12:30 to 13:30 -- Lunch
13:30 to 14:45 Deepa Agashe (NCBS, India) Tutorial: designing evolution experiments, model systems
14:45 to 15:00 -- Short break
15:00 to 16:15 Uma Ramakrishnan (NCBS, India) problem set with selection
16:15 to 16:30 -- Tea/coffee break
16:30 -- Free time
Sunday, 10 February 2019
Time Speaker Title Resources
09:30 to 10:45 -- Student presentations
10:45 to 11:15 -- Tea/coffee break
11:15 to 12:30 -- Student presentations