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Monday, 04 February 2019
Time Speaker Title Resources
09:30 to 10:45 Mrudula Basic elements of genetics and evolution: Genes, genomes, central dogma, polymorphism, genotype-phenotype correlation, inheritance
10:45 to 11:15 -- Tea/coffee break
11:15 to 12:30 Archana (Basic Math lecture): calculus, vectors/matrices, probabiity distributions
12:30 to 13:30 -- Lunch
13:30 to 14:45 Deepa Agashe Problem set: Mendelian genetics, selection, mutations
14:45 to 15:00 -- Short break
15:00 to 16:15 Archana Basic Math tutorial
16:15 to 16:30 -- Tea/coffee break
16:30 Deepa Agashe Journal club: Discuss Rainey and Travisano 1998
Tuesday, 05 February 2019
Time Speaker Title Resources
09:30 to 10:45 Vishwesha Guttal Process of model building. Discrete-time population dynamical models: density-dependent and density-independent growth
10:45 to 11:15 -- Tea/coffee break
11:15 to 12:30 Uma Ramakrishnan Hardy-Weinberg equilibirum; estimating allele frequencies
12:30 to 13:30 -- Lunch
13:30 to 14:45 Vishwesha Guttal Discrete-time logistic population model; linear stability analysis
14:45 to 15:00 -- Short break
15:00 to 16:15 Uma Ramakrishnan Basics of drift and migration. sampling and allele freq; Fst and wahlund effect
16:15 to 16:30 -- Tea/coffee break
16:30 Sumithra Computer simulations of logistic population model. Discuss May 1976
Wednesday, 06 February 2019
Time Speaker Title Resources
09:30 to 10:45 Vishwesha Guttal Discuss the proess of model building, purpose of models in light of results of logistic model. Introduce continuous time models
10:45 to 11:15 -- Tea/coffee break
11:15 to 12:30 Deepa Agashe Processes generating variation: Mutations, mutation rate, recombination, plasticity
12:30 to 13:30 -- Lunch
13:30 to 14:45 Vishwesha Guttal Game theory: hawk-dove games, selfishness and cooperation
14:45 to 15:00 -- Short break
15:00 to 16:15 Deepa Agashe Problem set: Measuring variation, experimental and bioinformatics approaches
16:15 to 16:30 -- Tea/coffee break
16:30 -- Free time
Thursday, 07 February 2019
Time Speaker Title Resources
09:30 to 10:45 Vishwesha Guttal Game theory: evolution of cooperation
10:45 to 11:15 -- Tea/coffee break
11:15 to 12:30 Kavita Jain Basic evol forces; Random genetic drift; Fixation probability; Neutral coalescent
12:30 to 13:30 -- Lunch
13:30 to 14:45 Vishwesha Guttal Game theory: exercises
14:45 to 15:00 -- Short break
15:00 to 16:15 Kavita Jain Problem set: Deterministic models
16:15 to 16:30 -- Tea/coffee break
16:30 Kavita Jain Journal club: Discuss Luria & Delbruck 1943, Servedio et al 2014
Friday, 08 February 2019
Time Speaker Title Resources
09:30 to 10:45 Uma Ramakrishnan Mutation and selection. Island-continent model and change in alelle freq. Different kinds of selection, w and w_bar; change in allele freq
10:45 to 11:15 -- Tea/coffee break
11:15 to 12:30 Uma Ramakrishnan problem set: HW. Migration/population structure
12:30 to 13:30 -- Lunch
13:30 to 14:45 Kavita Jain Adaptation dynamics (Lenski experiment, clonal interference, epistasis)
14:45 to 15:00 -- Short break
15:00 to 16:15 Kavita Jain Discussion of homework problems
16:15 to 16:30 -- Tea/coffee break
16:30 Uma Ramakrishnan Journal club: Discuss Foerster et al 2007, Rubidge et al 2012, and Barrett et al 2008
Saturday, 09 February 2019
Time Speaker Title Resources
09:30 to 10:45 Deepa Agashe Genome evolution: codon use, composition, copy number variation, non-coding sequences, epistasis, selfish elements
09:30 to 10:45 -- Tea/coffee break
11:15 to 12:30 Uma Ramakrishnan Simulations with drift, explore colaescent models and micro-evol processes under coalsecent
12:30 to 13:30 -- Lunch
13:30 to 14:45 Deepa Agashe Tutorial: designing evolution experiments, model systems
14:45 to 15:00 -- Short break
15:00 to 16:15 Uma Ramakrishnan problem set with selection
16:15 to 16:30 -- Tea/coffee break
16:30 -- Free time
Sunday, 10 February 2019
Time Speaker Title Resources
09:30 to 10:45 -- Student presentations
10:45 to 11:15 -- Tea/coffee break
11:15 to 12:30 -- Student presentations