The genome of the influenza virus consists of eight distinct single-stranded RNA segments, each encoding proteins essential for the viral life cycle. When the virus infects a host cell, these segments must be replicated and packaged into new budding virions. The viral genome is assembled with remarkably high fidelity: experiments reveal that most virions contain precisely one copy of each of the eight RNA segments. We use ideas from graph theory and self-assembly theory to figure out how the virus is able to achieve this.
Mukund Thattai (National Center For Biological Sciences)
Date & Time
Fri, 06 December 2019, 16:00 to 17:30
Ramanujan Lecture Hall, ICTS-TIFR, Bangalore