| Time | Speaker | Title | Resources | |
|---|---|---|---|---|
| 14:30 to 15:30 | -- | Registration | ||
| 15:30 to 18:30 | -- | Pre-School Tutorial: Krishanu Ray and Roop Mallik, Advanced microscopic techniques, fast, time lapse imaging of live preparations, and force measurements in situ | ||
| 18:30 to 19:30 | -- | Refreshments, Student-Teacher meeting, Welcome Dinner |
| Time | Speaker | Title | Resources | |
|---|---|---|---|---|
| 08:30 to 09:00 | Krishanu Ray/Dulal Panda (TIFR, Mumbai, India & IITB, India) | Opening remarks | ||
| 09:00 to 10:00 | Scott Brady (University of Illinois at Chicago, USA) | Neuron structure-function and historical research on axonal transport | ||
| 10:00 to 11:00 | Bill Saxton (UCSC, USA) | Motor Proteins-biophysical characteristics and force generation mechanisms | ||
| 11:00 to 11:30 | -- | Tea/Coffee | ||
| 11:30 to 13:00 | Roop Mallik (TIFR, Mumbai, India) | Biopysical Measurements of Motor function | ||
| 13:00 to 14:00 | -- | Lunch | ||
| 14:00 to 16:00 | Bill Saxton, Scott Brady and Sandhya Koushika (UCSC, USA, University of Illinois at Chicago, USA & NCBS, India) | Tutorial Session 1: Axonal Transport and Synapse assembly | ||
| 16:00 to 19:00 | -- | Assignment Session 1 | ||
| 19:00 to 20:00 | -- | Dinner |
| Time | Speaker | Title | Resources | |
|---|---|---|---|---|
| 09:00 to 10:00 | Dulal Panda (IITB, India) | Microtubule-form monomer to polymer and back | ||
| 10:00 to 11:00 | Ranjith P (IITB, India) | Basics of Monte Carlo Simulations | ||
| 11:00 to 11:30 | -- | Tea/Coffee | ||
| 11:30 to 13:00 | Gautam Menon (NUS, Singapore and IMSc, India) | Diffusion, Noise, and Brownian Motion: Concepts and Simple Estimates from Models relevant to Motors | ||
| 13:00 to 14:00 | -- | Lunch | ||
| 14:00 to 16:00 | Gautam Menon and Ranjith P (NUS, Singapore and IMSc, India and IITB, India) | Tutorial Session 2: Monte Carlo Simulations of CytoskeletalDynamics | ||
| 16:00 to 19:00 | -- | Assignment Session 2 | ||
| 19:00 to 20:00 | -- | Dinner |
| Time | Speaker | Title | Resources | |
|---|---|---|---|---|
| 09:00 to 10:00 | Bill Saxton (UCSC, USA) | Direct observation of organelle transportin axons and questions about transport mechanisms | ||
| 10:00 to 11:00 | Scott Brady (University of Illinois at Chicago, USA) | Regulation of fast axonal transport in health and disease | ||
| 11:00 to 11:30 | -- | Tea/Coffee | ||
| 11:30 to 13:00 | Krishanu Ray (TIFR, Mumbai, India) | Kinesin-2: A unique hetertrimeric motor | ||
| 13:00 to 14:00 | -- | Lunch | ||
| 14:00 to 16:00 | Dulal Panda (IITB, India) | Tutorial Session 3: Biochemical and biophysical techniques for assessing large macromolecular structures | ||
| 16:00 to 19:00 | -- | Assignment Session 3 | ||
| 19:00 to 20:00 | -- | Dinner |
| Time | Speaker | Title | Resources | |
|---|---|---|---|---|
| 09:00 to 10:00 | Ambarish Kunwar (IITB, India) | Computational Techniques to Understand Single Motors | ||
| 10:00 to 11:00 | Roop Mallik (TIFR, Mumbai, India) | Force measurements on a single motor protein | ||
| 11:00 to 11:30 | -- | Tea/Coffee | ||
| 11:30 to 13:00 | Pramod Pullarkat (RRI, India) | Cellular force measurements | ||
| 13:00 to 14:00 | -- | Lunch | ||
| 14:00 to 16:00 | Ambarish Kunwar and Roop Mallik (IITB, India & TIFR, Mumbai, India) | Tutorial Session 4: Modeling the crossover from Singleto Collectives of Motors | ||
| 16:00 to 19:00 | -- | Assignment Session 4 | ||
| 19:00 to 20:00 | -- | Dinner |
| Time | Speaker | Title | Resources | |
|---|---|---|---|---|
| 09:00 to 10:00 | Peter Hollenbeck (Purdue University, USA) | Historical perspectives and current questions on axonal transport mechanisms - regulation | ||
| 10:00 to 11:00 | Peter Baas (Drexel University, USA) | Microtubule organization in neurons, neuron development and disease | ||
| 11:00 to 11:30 | -- | Tea/Coffee | ||
| 11:30 to 13:00 | John Mercer (NCBS, India) | Intracellular transport by (and other functions of) Myosins | ||
| 13:00 to 14:00 | -- | Lunch | ||
| 14:00 to 15:50 | Subhojit Roy (UCSD, USA) | Human neurodegenerative neuropathology -the template for asking the right questions | ||
| 15:00 to 15:30 | -- | Break | ||
| 15:30 to 19:00 | Scott Brady and Subhojit Roy (University of Illinois at Chicago, USA & UCSD, USA) | Tutorial Session 5: Tools to explore axonaltransport in mice and squid - Application to Alzheimer's and Parkinson's disease | ||
| 19:00 to 20:00 | -- | Dinner |
| Time | Speaker | Title | Resources | |
|---|---|---|---|---|
| -- | Assessment Break (Free day) |
| Time | Speaker | Title | Resources | |
|---|---|---|---|---|
| 05:00 to 12:30 | -- | Departure to Mahabaleshar from IIT-B, Powai | ||
| 12:30 to 13:50 | -- | Lunch (The Club, Mahabaleshwar) | ||
| 13:50 to 14:00 | Krishanu Ray/Subhojit Roy (TIFR, Mumbai, India & UCSD, USA) | Opening remarks | ||
| 14:00 to 15:00 | Roop Mallik (TIFR, Mumbai, India) | Tug of War: Motors Fight it out inside a cell | ||
| 15:00 to 16:00 | Gautam Menon (NUS, Singapore and IMSc, Chennai) | Simple Models for Axonal Transports | ||
| 16:00 to 16:30 | -- | Tea/Coffee Break | ||
| 16:30 to 18:00 | Promod Pullarkat (RRI, India) | Shape instabilities in axons | ||
| 18:00 to 19:00 | Gautam Menon and Roop Mallik (NUS, Singapore and IMSc, India & TIFR, Mumbai, India) | Discussion Group1: (Presentations,of Tutorial 4 assignments) | ||
| 19:00 to 20:00 | -- | Dinner | ||
| 20:00 to 21:00 | John Mercer (NCBS, India) | Myosin V at the synapse and in RNA transport between cells |
| Time | Speaker | Title | Resources | |
|---|---|---|---|---|
| 09:00 to 10:00 | Scott Brady (University of Illinois at Chicago, USA) | Adult-Onset Neurodegeneration as Dysferopathies | ||
| 10:00 to 11:00 | Bill Saxton (UCSC, USA) | Cytoplasmic streaming: how motors can move fluid | ||
| 11:00 to 11:30 | -- | Tea/Coffee | ||
| 11:30 to 13:00 | Peter Hollenbeck (urdue University, USA) | Mitochondrial Transport, Metabolism and ROS Production in Disease Models | ||
| 13:00 to 14:00 | -- | Lunch | ||
| 14:00 to 16:00 | Subhojit Roy, Peter Baas and Peter Hollenbeck (UCSD, USA, Drexel University, USA and Purdue University, USA) | Discussion Group 2: (Presentations of Tutorial 1 and 5 assignments) | ||
| 16:00 to 19:00 | -- | Outdoor Break | ||
| 19:00 to 20:00 | -- | Dinner | ||
| 20:00 to 21:00 | Peter Baas (Drexel University, USA) | Microtubule Polarity Orientation in Neurons: The Story behind the Story |
| Time | Speaker | Title | Resources | |
|---|---|---|---|---|
| 09:00 to 10:00 | Anna Akhmanova (Utrecht University, Netherlands) | Regulation of microtubule dynamics | ||
| 10:00 to 11:00 | Dulal Panda (IITB, India) | Unusual MAPs and Microtubule assembly in vivo | ||
| 11:00 to 11:30 | -- | Tea/Coffee | ||
| 11:30 to 13:00 | Anna Akhmanova (Utrecht University, Netherlands) | A zoo at the tip: a dynamic protein network controls the fate of microtubule ends | ||
| 13:00 to 14:00 | -- | Lunch | ||
| 14:00 to 16:00 | Anna Akhmanova, Michel Steinmetz and Dulal Panda (Utrecht University, Netherlands, Paul Scherrer Institut, Switzerland & IITB, India) | Discussion Group 4: (Presentations, assignments of Tutorial 3) | ||
| 16:00 to 16:45 | -- | Tea/Coffee | ||
| 16:45 to 19:00 | -- | Poster Session I | ||
| 19:00 to 20:00 | -- | Dinner | ||
| 20:00 to 21:00 | Michel Steinmetz (Paul Scherrer Institut, Switzerland) | Molecular mechanisms of microtubule tip tracking |
| Time | Speaker | Title | Resources | |
|---|---|---|---|---|
| 09:00 to 10:00 | Subhojit Roy (UCSD, USA) | The Curious Case of the Soluble Protein: A new paradigm in axonal transport | ||
| 10:00 to 11:00 | Peter Baas (Drexel University, USA) | Microtubule-Severing Proteins in the Axon: Implications for Degeneration and Regeneration | ||
| 11:00 to 11:30 | -- | Tea/Coffee | ||
| 11:30 to 13:00 | Peter Hollenbeck (Purdue University, USA) | Location and Organization of Features ofthe Mitochondrial Life Cycle in Neurons | ||
| 13:00 to 14:00 | -- | Lunch | ||
| 14:00 to 15:00 | Peter Baas (Drexel University, USA) | Mitotic Motors co-Regulate MicrotubuleOrganization in Axons and Dendrites | ||
| 15:00 to 16:45 | -- | Outdoor Break | ||
| 16:45 to 19:00 | -- | Poster Session II | ||
| 19:00 to 20:00 | -- | Dinner | ||
| 20:00 to 21:00 | Krishanu Ray (TIFR, Mumbai, India) | Selective Axonal Transports by Kinesin-2 |
| Time | Speaker | Title | Resources | |
|---|---|---|---|---|
| 09:00 to 10:00 | Yishi Jin (UCSD, USA) | Genetic approaches to synapse formation | ||
| 10:00 to 11:00 | Sandhya Koushika (NCBS, India) | Regulation of synaptic vesicle transport | ||
| 11:00 to 11:30 | -- | Tea/Coffee | ||
| 11:30 to 13:00 | Yishi Jin (UCSD, USA) | From synapse formation to axonregeneration: tale of a kinase | ||
| 13:00 to 14:00 | -- | Lunch | ||
| 14:00 to 16:00 | Yishi Jin and Sandhya Koushika (UCSD, USA & NCBS, India) | Discussion Group 3: (Presentations of Tutorial 1 assignments) | ||
| 16:00 to 16:15 | -- | Tea/Coffee | ||
| 16:15 to 18:30 | -- | Platform presentations by students on their research work (10 min each) | ||
| 18:30 to 19:00 | -- | Valedictory session | ||
| 19:00 to 20:00 | -- | Dinner | ||
| 20:00 to 21:00 | -- | Bon Fire |
| Time | Speaker | Title | Resources | |
|---|---|---|---|---|
| 13:00 to 14:30 | -- | Departure from Mahabaleshwar (after lunch) | ||
| 14:30 to 19:30 | -- | Arrival in Pune | ||
| 19:30 to 20:30 | -- | Arrival in Mumbai |
| Time | Speaker | Title | Resources | |
|---|---|---|---|---|
| -- | M2t2 meeting in Mumbai |